HYBRIDOMAS OBTAINED FROM TRANSGENIC ANIMAL LYMPHOCYTES CARRYING A GENE EXPRESSING A SPECIFIED PROTEIN AND PROCESS FOR THE PREPARATION OF SUCH PROTEIN FROM SUCH HYBRIDOMAS

摘要

Tissue cell culture preparations derived from the cells of a transgenic animal are disclosed. These tissue cell preparations are capable of expressing a non-analogous gene product, i.e., a gene product which is not naturally produced by the animal cells. Transhybridomas, i.e., hybridomas and immortalized cells created using cells obtained from transgenic animals, and methods for creating these transhybridomas are also disclosed. In particular, two transhybridomas, A 15.9 and B 6.4, both capable of producing human growth hormone, have been disclosed.