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METHOD OF IMMUNITY ANALYSIS AND REAGENT FOR IMMUNITY ANALYSIS

机译:免疫分析方法和免疫分析试剂

摘要

PURPOSE:To make it possible to perform precise immunity analysis by using a first physiological active material comprising a part of an antibody, and using a second physiological active material which contains the same molecular structure as the first material and which is fixed through a pretreating reagent and fixing agent. CONSTITUTION:The following materials are used: a first liposome comprising phospholipid or glycolipid; a first physiological active material which is fixed to the liposome through a fixing agent and has antigen-antibody reactivity with a material under test in a sample; and a testing reagent comprising a label material which is sealed in the first liposome. The testing reagent and a complement are inputted into the sample and made to react with the material under test. The obtained label material is measured, and the material under test is determined. When a part of an antibody is used as the first physiological material, it is desirable to fix a second physiological active material that does not undergo antigen-antibody reaction with the material under test in the sample on the liposome through the same fixing agent used in the test reagent. The second physiological active material contains the same molecular structure as at least a part of the antibody in a pretreating reagent.
机译:目的:通过使用包含一部分抗体的第一生理活性物质,以及使用与第一物质具有相同分子结构并通过预处理试剂固定的第二生理活性物质,可以进行精确的免疫分析和固定剂。组成:使用以下材料:第一脂质体,其包含磷脂或糖脂;第一生理活性材料,其通过固定剂固定在脂质体上,并且与样品中的被测材料具有抗原-抗体反应性;包含密封在第一脂质体中的标记材料的测试试剂。将测试试剂和补体输入样品中,并使其与被测材料发生反应。测量获得的标签材料,并确定被测材料。当将抗体的一部分用作第一生理材料时,期望通过脂质体中使用的相同的固定剂将不与样品中的被测材料发生抗原-抗体反应的第二生理活性材料固定在脂质体上。测试试剂。第二生理活性物质在预处理试剂中包含与抗体的至少一部分相同的分子结构。

著录项

  • 公开/公告号JPH02262060A

    专利类型

  • 公开/公告日1990-10-24

    原文格式PDF

  • 申请/专利权人 TOSHIBA CORP;

    申请/专利号JP19890081411

  • 发明设计人 ISHIMORI YOSHIO;

    申请日1989-04-03

  • 分类号G01N33/544;

  • 国家 JP

  • 入库时间 2022-08-22 06:25:20

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