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PROCESS FOR PRODUCING MIXED SUBSTITUTED PHOSPHATIDYL CHOLINES AND PHOSPHATIDYL ETHANOLAMINES
PROCESS FOR PRODUCING MIXED SUBSTITUTED PHOSPHATIDYL CHOLINES AND PHOSPHATIDYL ETHANOLAMINES
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机译:制备混合取代的磷脂酰胆碱和磷脂酰乙醇胺的方法
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摘要
The invention relates to new triphenylmethyl derivatives of sn-glycero-3-phosphocholine and sn-glycero-3-phosphoethanolamine of the general formula IMAGE I in which T denotes a triphenylmethyl group which is unsubstituted or monosubstituted or polysubstituted by C1-C6-alkyl, C1-C6-alkoxy or halogen, and the radicals R1, R2 and R3 either are identical and each represent a methyl group, or are different, in which case two of the radicals R1, R2 and R3 always denote hydrogen, and the third radical represents a triphenylmethyl group which is unsubstituted or monosubstituted or polysubstituted by C1-C6-alkyl, C1-C6-alkoxy or halogen, a process for their preparation, and their use for the preparation of chemically defined pure enantiomeric 1,2-diacyl-sn-glycero-3-phosphocholines and 1,2-diacyl-sn-glycero-3-phosphoethanolamines which are substituted in positions 1 and 2 of the glycerol, independently of one another, by different acyl radicals.
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