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A METHOD FOR THE TOTAL SYNTHESIS OF CYCLOSPORINS, NOVEL CYCLOSPORINS AND NOVEL INTERMEDIATES AND METHODS FOR THEIR PRODUCTION
A METHOD FOR THE TOTAL SYNTHESIS OF CYCLOSPORINS, NOVEL CYCLOSPORINS AND NOVEL INTERMEDIATES AND METHODS FOR THEIR PRODUCTION
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机译:环孢菌素,新型环孢菌素和新型中间体的总合成方法及其生产方法
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摘要
Novel [1S, 2R, 3R]- and [1R, 2S, 3S)-1-nitrilo-1-carbonyl-3-methyl-2-oxy-heptanes and -hept-5-enes. Such compounds are useful in the total synthesis of cyclosporins, in particular cyclosporin A, e.g. applying the method described and claimed in co-pending European Patent Application No. 81 810 043.0.
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