FREMGANGSMAATE FOR BEHANDLING AV TANNROTSYKDOM VED VEDVARENDE AVGIVELSE AV ET FARMASOEYTISK MIDDEL TIL CREVIKULARLOMMEN, STOFFBLANDING FOR DETTE OG APPARAT FOR ADMINISTRERING DERAV.

摘要

Oral compositions for the local administra­tion of a therapeutic agent to a periodontal pocket of a patient for alleviating dental disease comprise a plurality of dry, discrete microparticles each of which comprise an effective amount of at least one thera­peutic agent dispersed in a matrix comprising a bio­compatible and biodegradable polymer. Apparatus and methods are also provided for the dispensing of the dry microparticles to the periodontal pocket whereby they become tacky and adhere to the involved tissue so as to induce long term therapeutic benefits.