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METHOD FOR PREPARING NEW HUMAN / BOVINE BASED FOBROBLAST GROWTH FACTOR DERIVATIVES
METHOD FOR PREPARING NEW HUMAN / BOVINE BASED FOBROBLAST GROWTH FACTOR DERIVATIVES
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机译:一种新的基于人/牛的成纤维细胞生长因子衍生物的制备方法
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摘要
The present invention relates to the production, by recombinant DNA techniques, of derivatives of basic fibroblast growth factor (bFGF). These derivatives of bFGF can act as antagonists and/or superagonists of the wild type molecule in the angiogenic process. These derivatives, as well as wild type bFGF, may be prepared by the use of strains or E. coli which have been transformed with plasmids carrying nucleotide sequence coding for human and bovine bFGF and their derivatives.
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