PROCESSES FOR THE PREPARATION THEREOF AND THE USE THEREOF IN SOLID PHASE REACTIONS

摘要

The solid-phase system has the general formula …IMAGE… in which F is a solid carrier material, R1 and R2 are identical or different and are hydrogen, alkyl, aryl or halogen, R3 is a spacer, X is hydroxyl, halogen, a sulphonate group, a phosphonate group or an acyloxy group, where acyl in the acyloxy group is the radical of an aliphatic carboxylic acid or the radical RCO- in which R is an organic radical which is bonded via the carbonyl group, and n is the number of side chains bonded to the carrier material, and is suitable for solid-phase reactions, in particular for solid-phase synthesis of peptides, glycopeptides, nucleotides or proteins.