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Anti-human lymphotoxin monoclonal antibody, hybridoma for production thereof, anti-human lymphotoxin-C-terminal peptide antibody and method for detecting human lymphotoxin thereby
Anti-human lymphotoxin monoclonal antibody, hybridoma for production thereof, anti-human lymphotoxin-C-terminal peptide antibody and method for detecting human lymphotoxin thereby
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机译:抗人淋巴毒素单克隆抗体,其产生的杂交瘤,抗人淋巴毒素-C-末端肽抗体及其检测人淋巴毒素的方法
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摘要
Disclosed are a human lymphotoxin-neutralizing monoclonal antibody-producing hybridoma, an anti-human lymphonotoxin monoclonal antibody produced by that hybridoma and an anti-human lymphotoxin neutralizing antibody. The hybridoma is obtained by fusing a myeloma cell with a spleen cell or a lymphonodus cell of an animal immunized with an N-terminal-deleted human lymphotoxin. The anti-human lymphotoxin neutralizing antibody is harvested from an animal immunized with a human LT-C-terminal peptide.;The two kinds of antibodies described above can be used for an immunochemical method for assaying a human lymphotoxin in a test solution, one as an antibody to be held on a carrier and the other as an antibody to be linked with a labeling agent.
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