首页> 外国专利> Use of solutions of atelocollagen and polyholosides, for example glycosaminoglycans, for the manufacture of microcapsules, microcapsules produced in this way, processes for the manufacture of such microcapsules and cosmetic, pharmaceutical or food compositions in which they are present

Use of solutions of atelocollagen and polyholosides, for example glycosaminoglycans, for the manufacture of microcapsules, microcapsules produced in this way, processes for the manufacture of such microcapsules and cosmetic, pharmaceutical or food compositions in which they are present

机译:端胶原蛋白和多糖苷(例如糖胺聚糖)溶液在制备微囊中的用途,以这种方式制备的微囊,制备此类微囊的方法以及存在它们的化妆品,药​​物或食品组合物

摘要

The invention relates to microcapsules with a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, and to processes for the manufacture of the said microcapsules.;According to the invention, the microcapsules comprise a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, the propor­tion of polyholosides, for example glycosaminoglycans, relative to the atelocollagen preferably being between 18 and 50% by weight. These microcapsules can be manufac­tured either by a process involving interfacial cross­linking or by the extrusion of a laminar flow which is broken up by vibrations into individual droplets, which fall into a crosslinking bath.;These microcapsules are biocompatible by virtue of the presence of atelocollagen, which has most of the advantageous properties of collagen, namely a very low antigenicity and a perfect biodegradability. They are therefore particularly suitable for the manufacture of cosmetic, pharmaceutical or food compositions.
机译:本发明涉及具有交联的端粒胶原蛋白和多元醇例如糖胺聚糖的混合壁的微囊,并且涉及所述微囊的制造方法。糖胺聚糖,相对于卤代胶原蛋白,多糖化物例如糖胺聚糖的比例优选为18-50重量%。这些微胶囊可以通过涉及界面交联的过程来制造,也可以通过层流的挤出来制造,该层流通过振动分解成单个液滴并落入交联浴中;这些微囊由于<!-EPO而具有生物相容性->存在Atelocollagen,它具有胶原蛋白的大多数优势,即极低的抗原性和完美的生物降解性。因此它们特别适合于制造化妆品,药​​物或食品组合物。

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