PROCESS FOR PRODUCING PEPTIDES BY SPECIFIC CLEAVAGE OF FUSION PROTEINS WITH COLLAGENASES OBTAINED BY GENETIC ENGINEERING

摘要

Are described fusion proteins having the formula (I): H2N-Z1-X- (Pro-Y-Gly) n-Z2-Pro-COOH, wherein n 2, X and Y represent each of the 20 amino acids determined by the genetic code, Z1 is a sequence of bacterial amino acid and Z 2 is the target peptide consisting of any desired amino acid genetic code. Process for their production and enzymatic cleavage, to form the desired eucaryotic protein, are also disclosed.