首页> 外国专利> Method for determining a gene locus of variable length in a DNA sequence and optionally labelled nucleotide sequences for identifying such a gene locus

Method for determining a gene locus of variable length in a DNA sequence and optionally labelled nucleotide sequences for identifying such a gene locus

机译:确定DNA序列和任选标记的核苷酸序列中可变长度的基因座以鉴定此类基因座的方法

摘要

A method for detecting the presence of an unknown locus of variable length in a DNA sequence with at least one known locus. The method can be used in particular for detecting informative gene loci, for example minisatellite or VNTR regions. The invention also relates to loci of variable length which are found by a method of this type, and to the corresponding hybridisation probes. The latter can be used in genetic characterisation methods and in the diagnosis and therapy of genetic disorders and cancer.
机译:一种用于检测具有至少一个已知基因座的DNA序列中可变长度的未知基因座的存在的方法。该方法尤其可以用于检测信息基因座,例如小卫星或VNTR区域。本发明还涉及通过这种方法发现的可变长度的基因座,以及相应的杂交探针。后者可用于遗传表征方法以及遗传疾病和癌症的诊断和治疗。

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