首页> 外国专利> REMEDY FOR NEONATAL HEMOLYTIC JAUNDICE

REMEDY FOR NEONATAL HEMOLYTIC JAUNDICE

机译:新生儿溶血性黄疸的补救措施

摘要

PURPOSE:To obtain the subject remedy, containing human gamma-globulin as an active ingredient and capable of exhibiting remarkable treating effects with high safety. CONSTITUTION:A remedy containing highly purified human gamma-globulin, having =20 units anticomplementary activity measured at 5% protein concentration and exhibiting =90% peaks of 7S in purity as IgG determined by cellulose acetate electrophoresis without virtually containing polymerization type gamma-globulin and preferably any blood type antibody as an active ingredient. The aforementioned remedy is normally prepared as a pharmaceutical in the form of a freeze-dried formulation and preferably simultaneously dissolved in an aqueous solvent so as to provide 10-100mg/ml expressed in terms of proteins and administered by intravenous dripping, injection, etc. The dose thereof is about 0.2-2g/kg at a time. The above-mentioned dose is administered in 1 to several divided portions a day for 1 to several days preferably in combination with phototherapy.
机译:目的:以人γ-球蛋白为有效成分,能够以高安全性表现出显着的治疗效果,从而获得本发明的治疗方法。组成:一种含有高度纯化的人γ-球蛋白的药物,在蛋白质浓度为5%时测得的抗互补活性为<= 20单位,通过醋酸纤维素电泳测定的IgG的IgG纯度为> = 90%的峰,而实际上不含聚合型γ-球蛋白,最好是任何血型抗体作为有效成分。上述药物通常以冻干制剂的形式制备为药物,并且优选同时溶解于水性溶剂中以提供10-100mg / ml的蛋白质表达并通过静脉滴注,注射等方式给药。一次的剂量约为0.2-2g / kg。上述剂量优选每天与光疗联用,每天分成1至数个部分,持续1至数天。

著录项

  • 公开/公告号JPH03163029A

    专利类型

  • 公开/公告日1991-07-15

    原文格式PDF

  • 申请/专利权人 GREEN CROSS CORP:THE;

    申请/专利号JP19900042021

  • 发明设计人 KONDO KEN;HARA TOSHIRO;

    申请日1990-02-22

  • 分类号A61K39/395;A61P1/16;

  • 国家 JP

  • 入库时间 2022-08-22 06:06:29

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号