NEW PLATINUM COMPLEX AND ANTITUMOR AGENT CONTAINING THE SAME PLATINUM COMPLEX AS ACTIVE INGREDIENT

摘要

NEW MATERIAL:A compound expressed by formula I (R represents formulae II or III; Ph represents phenyl). EXAMPLE:[1,2-Bis(diphenylphosphino)ethane](1R,2R-cyclohexanediamine)pa lladium (II) nitrate. USE:An antitumor agent. PREPARATION:A cyclohexanediamine palladium (II) nitrate [Pd(NO3)2(R,R-dach)] or 1,2-bis(diphenylphosphino)ethanepalladium (II) chloride [PdCl2(DPPE)] is dissolved or dispersed in water and 1,2-bis-(diphenylphosphino)ethane or ethylenediamine is then added and reacted for 30min to 5hr. After completing the reaction, the resultant product is cooled and precipitated.