procedure for the production of an antibody or antiserum, the use of this procedure for the acquisition of mammalian cells, which are able to produce such a antibodyand the use of the thus manufactured antibody or antiserum to immunoassay.

摘要

an antibody with a high specificity for a first antigen, which is a desired antigenic determinant at low vernetzungsreaktivitu00e4t with at least one other antigen has at least one of the desired antigenic determinant which the first antigen structurally related a ntigene determinant contains, is thereby producedthat a mammal a copolymer of d and d - glutamic acid lysine is given, which is coupled with the other antigen is thus essentially a effective immunological tolerance is induced and the mammal with the first antigen immunized. the erfindungsgemu00e4u00dfe procedure leads to the production of strains which are able to produce the desired antibody.these strains can after removal of its host is independently used to the desired to produce antibodies. the so obtained antibodies have a very low vernetzungsreaktivitu00e4t and high specificity, and are particularly useful as specific antibodies for the immunopru00fcfung of various substances in the human body.