Polynucleotide and purified polypeptide DNA vector host cell processes to produce mdc to produce a mdc polypeptide analogue to modulate leukocyte chemotaxis in a mammalian host to relieve an inflammatory fission in a patient and to identify a chemical compound antibody lineage of a cell from polyclonal antiserum hybridoma and pharmaceutical composition and use of composition

摘要

The present invention provides purified and isolated polynucleotide sequences encoding a novel human macrophage-derived C-C chemokine designated MDC, and polypeptide analogs thereof. Also provided are materials and methods for the recombinant production of the chemokine, and purified and isolated chemokine protein, and polypeptide analogs thereof.