IN VIVO ANIMAL MODEL FOR STUDYING ALZHEIMER'S DISEASE

摘要

In vivo mouse model for studying Alzheimer's disease is produced by introducing Trisomy 16 mouse embryonic central nervous system (CNS) tissues to the brain of a live host mouse. The neuropathology in the introduced Trisomy 16 CNS tissues closely parallels that of human Alzheimer's disease, so that the host mouse with such introduced tissues provides a potentially useful living animal model in which to study the development of Alzheimer's disease and in which to test potential preventative or curative treatments.