A PROTEIN FAMILY RELATED TO IMMEDIATE-EARLY PROTEIN EXPRESSED BY HUMAN ENDOTHELIAL CELLS DURING DIFFERENTIATION

摘要

This invention provides a novel family of tissue specific genes and proteins that are related to a G-protein-coupled receptor gene and the receptor protein. The gene is an intermediate early gene that is expressed in differentiating endothelial cells. In particular, this invention provides a gene, edg-1, that is an immediate-early gene that encodes a G-protein-coupled receptor in endothelial cells. This invention also provides the G-protein-coupled receptor protein that is encoded by edg-1.