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HORNERIN: A NOVEL NON-VEGF MEDIATED ANGIOGENIC PROTEIN EXPRESSED IN BOTH HUMAN AND MOUSE ANGIOGENIC ENDOTHELIAL CELLS AND HUMAN PANCREATIC CANCER CELLS
HORNERIN: A NOVEL NON-VEGF MEDIATED ANGIOGENIC PROTEIN EXPRESSED IN BOTH HUMAN AND MOUSE ANGIOGENIC ENDOTHELIAL CELLS AND HUMAN PANCREATIC CANCER CELLS
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机译:角质素:在人和小鼠血管内皮细胞和人类胰腺癌细胞中均表达的新型非VEGF介导的血管生成蛋白
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摘要
Provided are compositions and methods for use of hornerin-binding molecules, including peptides and antibodies. In some embodiments, the presently disclosed subject matter provides compositions that include horning-binding molecules, including but not limited to peptides, uses for the disclosed compositions, including in methods for treating tumors, methods for increasing the survival of subject with tumor, methods for suppressing tumor growth in subjects, methods for reducing tumor vascularity in subjects, methods for treating diseases, disorders, and/or conditions associated with undesirable hornerin expression; methods for modulating hornerin biological activities, methods for imaging cells, tissues, and/or organs that expresses hornerin, and methods for delivering active agents to cells, tissues, and/or organ that expresses hornerin.
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