Increased expression of small molecular weight recombinant proteins

摘要

The present invention discloses novel DNA sequences encoding protein derivatives that allow for high expression of small molecular weight recombinant proteins. Once the desired protein derivatives are obtained, the extra amino acid sequence can be cleaved to yield native protein. The sequence encoding methionine-x-x′-protein, wherein x and x′ are selected from the group consisting of phenylalanine, leucine, isoleucine, methionine, valine, serine, proline, threonine, alanine, tyrosine, histidine, glutamine, aparagine, lysine, apartic acid, glutaminc acid cysteine, tryptophane, arginine and glycine.