Method for the inhibition of cell-cell and cell substratum interactions by the blocking of carbohydrate-carbohydrate interactions

摘要

Methods for the inhibition of cell-cell and cell-­substratum interactions by the blocking of carbohydrate-­carbohydrate interactions are disclosed. Inhibition of cell-­cell and cell-substratum interactions by the methods of the present invention permit the inhibition of a variety of biological phenomena, including metastases, mammalian diseases that are microbial in origin, mammalian fertilization, and plant pathologies. Suitable agents for blocking carbohydrate-­carbohydrate interactions include saccharides, glycocon­jugates, and antibodies directed against carbohydrate determinants.