Extracts from Ginkgo biloba leaves - with high content of flavone glycoside(s) and ginkgolide(s) but with low alkyl phenol(s) content

摘要

Novel extracts from the leaves of Ginkgo biloba are practically free from alkyl phenols, have a high content of flavone glycosides and contain most of the ginkgolides and bilobalide originally present in the leaves. Pref. the extracts contain 14-22 (esp. 16-18) wt.% flavone glycosides, 1.6-3wt.% total ginkgolides A, B, C and J, 1.4-2.7 wt.% bilobalide and less than 10 ppm (esp. less than 1 ppm) alkyl phenols. USE/ADVANTAGE - The extracts promote circulation, inhibit ischaemic damage and aggregation of radical acceptors and thrombocytes. The extracts are esp. useful in the therapy of peripheral and cerebral arterial disorders of the circulation. Removal of the alkyl phenols (which are associated with allergies) is achieved without the need to use the chlorinated hydrocarbons necessary in previous processes and thus the associated risks to the environment and the presence of residues in the pharmaceutical are avoided.