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NMR-KONTRASTMIDDEL INDEHOLDENDE MINDST ET VANDOPLOESELIGT, PARAMAGNETISK IKKE-RADIOAKTIVT METALCHELAT, SAMT ET SAADANT CHELAT OG DETS ANVENDELSE
NMR-KONTRASTMIDDEL INDEHOLDENDE MINDST ET VANDOPLOESELIGT, PARAMAGNETISK IKKE-RADIOAKTIVT METALCHELAT, SAMT ET SAADANT CHELAT OG DETS ANVENDELSE
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机译:至少包含水溶性,顺磁性非放射性金属螯合物和此类螯合物的NMR对比剂及其用途
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摘要
There are provided NMR contrast agents comprising water-soluble paramagnetic metal chelates, preferably of Cr(III), Fe(III) or Gd(III), wherein the chelating entity is an anilide group containing organic moiety, preferably a compound of formula I IMAGE (I) wherein R1 to R5 may represent hydrogen or halogen atoms, optionally halogenated alkyl or alkoxy groups or carboxyl groups. The agents are especially suitable for use in NMR imaging of the hepatobiliary system.
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