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PROCESS FOR THE PRODUCTION OF MEDICAL PREPARATIONS WITH REHYDRATING EFFECT, STABILIZED BY THE NEW CRYSTALLIZED FORM OF ALCALI-HYDROGEN-CARBONATE
PROCESS FOR THE PRODUCTION OF MEDICAL PREPARATIONS WITH REHYDRATING EFFECT, STABILIZED BY THE NEW CRYSTALLIZED FORM OF ALCALI-HYDROGEN-CARBONATE
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机译:具有新型结晶形式的氢氧化铝-碳酸盐稳定化的具有保湿作用的药物制剂的生产过程
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Dehydrating and simultaneously resalinating medicinal mixts. stabilised by alkali-hydrogen-carbonate(s) of new crystalline forms(s) contain: 90 (Sic-no units provided) sodium, 20 potassium, 80 chloride, 30 hydrogen carbonate, 110 glucose and/or water sol. salts of other metals pref 0.2-2.5 magnesium or calcium (or both in combination). The quoted values are to be dissolved in 1 dm/3 of water. Other overall quantities may be used provided m molar ratios are maintained in the mixts.. Alkali-hydrogen carbonates are present in these mixts. either as an isomorphic crystalline modification of carbon-dioxide satd. sodium-hydrogen-carbonate or as a heteromorphic, non-stoichiometric modification, obtd. from carbon dioxide satd. 0.25-2 mols of potassium-hydrogen-carbonate and 1 mol sodium-hydrogen-carbonate, by compressor. Alkali-hydrogen-carbonates are added to the mix in granular form of 177-841 micro-m. size; The size range of added anhydrous glucose is 250-1000 microns. Foregoing components are mixed with anhydrous alkali-chlorides and opt. flavouring and colouring agents, and are administered dissolved in water.
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