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SYNTHETIC PEPTIDES FOR DETOXIFICATION OF BACTERIAL¹ENDOTOXINS AND FOR THE PREVENTION AND TREATMENT OF SEPTIC¹SHOCK
SYNTHETIC PEPTIDES FOR DETOXIFICATION OF BACTERIAL¹ENDOTOXINS AND FOR THE PREVENTION AND TREATMENT OF SEPTIC¹SHOCK
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机译:合成肽对细菌内毒素的解毒作用及预防和治疗脓毒症
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摘要
The present invention provides methods of using peptides of the formula R1-(A-B-C)n-R, wherein R1 and R are independently H or an amino acid residue or a fatty acid residue; A is an amino acid residue selected from the group consisting of Lys and Arg; B is an amino acid selected from the group consisting of Phe, Tyr, and Trp; C is an amino acid selected from the group consisting of Leu, Ile and Val; n is an integer of 1-100. The peptides are used for the removal of endotoxin from blood or sera; the detoxification of bacterial endotoxin; and the prevention of the contamination of products with endotoxin.
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