A B S T R A C TThis invention relates to new stereochemically pure andstable adducts of Z-1-(p-.beta.-dimethylaminoetlloxyl)henyl)-1-(p-hydroxyphenyl)-2-phenyl-but-1-ene and certain solventswhich by virtue of their marked antioestrogenic activitiesmay be used for the therapeutic treatment of benign breastdiseases and hormone-dependent mammary tumours, inparticular by percutaneous application.
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机译:A B S T R A C T本发明涉及新的立体化学纯和Z-1-(对-β-二甲基氨基乙氧基)henyl)-1-的稳定加合物(对羟基苯基)-2-苯基丁-1-烯和某些溶剂凭借其显着的抗雌激素活性可用于良性乳房的治疗疾病和激素依赖性乳腺肿瘤特别是经皮应用。
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