ANTIPLATELET AND ANTITHROMBOTIC ACTIVITY OF PLATELET GLYCOPROTEIN IB RECEPTOR FRAGMENTS

摘要

A platelet glycoprotein Ib receptor fragment, having antiplatelet and antithrombotic activity, is useful for blocking platelet adhesion. The fragment inhibits the binding of von Willebrand's Factor to platelets. The invention may be used in the treatment of patients who are particularly prone to thrombosis and embolism. The invention may also be used to purify von Willebrand's Factor.