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Use of L-2-oxothiazolidine-4-carboxylate alone or in combination with glutathione esters and/or amino acids in the treatment of reperfusion injury

机译:L-2-氧噻唑烷-4-羧酸盐单独或与谷胱甘肽酯和/或氨基酸组合用于治疗再灌注损伤的用途

摘要

The use of L-2-oxothiazolidine-4-carboxylate alone or in combination with glutathione esters and/or amino acids for the preparation of a composition for treating and/or reducing ischemic reperfusion injury. To this end, in embodiment, the composition is used for treating and/or reducing reperfusion injury in a patient in danger of reperfusion injury. In an embodiment, the composition is used for limiting an expected ischemic reperfusion injury in a patient prior to an expected ischemic event. In a further embodiment of the present invention, the composition is used for limiting ischemic reperfusion injury in a patient after the onset of an ischemic event.
机译:单独或与谷胱甘肽酯和/或氨基酸组合的L-2-氧噻唑烷-4-羧酸酯在制备用于治疗和/或减轻缺血性再灌注损伤的组合物中的用途。为此,在实施方案中,该组合物用于治疗和/或减少处于有再灌注损伤危险的患者中的再灌注损伤。在一个实施方案中,该组合物用于在预期的缺血事件之前限制患者的预期的缺血再灌注损伤。在本发明的另一个实施方案中,该组合物用于在局部缺血事件发作后限制患者的局部缺血再灌注损伤。

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