METHOD FOR PREPARATION OF STRAIN STREPTOCOCCUS SANGUIS, WHICH IS ABLE TO PRODUCE @@@-1,3-GLUCAN-3-GLUCANOHYDROLASE

摘要

Disclosed is the isolation and cloning of genes encoding glucanohydrolase enzymes and the expression and secretion of exogenous glucanase gene products in host cells. Disclosed also are dental caries preventative preparations and methods for their preparation and use which involve microbial host cells indigenous to the oral cavity transformed to express and secrete glucanase gene products.