Pharmaceutical compositions containing cytidine monophosphate of 5- acetamido-3-, 5-D-deoxy-D-glycero-D-galacto-nonulosamic acid
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机译:包含5-乙酰氨基-3-,5-D-脱氧-D-甘油-D-半乳糖醛酸的胞苷一磷酸的药物组合物
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摘要
The invention relates to pharmaceutical compositions for use in the therapy of pathological states related to disturbances of the nervous stimulus in the central (CNS) and peripheral (PNS) nervous system containing as an active substance the cytidine monophosphate of 5- acetamido-3,5-dideoxy-D-glycero-D-galactono-nulosaminic acid. Moreover the invention relates to an improved method for preparing said compound by the condensation of cytidine triphosphate (CTP) with N- acetylneuraminic acid (NANA), catalyzed by the enzyme CMP-transferase (CMP-acylneuraminate synthase) (EC 2.7.7.43).
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