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Azole mycocide and method of treating mycosis

机译:唑类杀菌剂和治疗霉菌病的方法

摘要

Disclosed herein are azole derivatives or the salts thereof which are represented by the general formula (I): ##STR1## wherein X represents a halogen atom, an alkyl group having 1 to 5 carbon atoms, a haloalkyl group, a phenyl group, a cyano group, or a nitro group, Xs being either the same or different from each other; n represents an integer of 1 to 5; A represents a nitrogen atom or CH; and one of R.sub.1 and R.sub.2 represents an alkyl group having 1 to 5 carbon atoms and the other a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, with the proviso that when n is 1 or 2, X does not represent a halogen atom, an alkyl group having 1 to 5 carbon atoms or a phenyl group, and mycocides comprising an effective amount of azole derivative or medically or veterinarily acceptable salt thereof, said azole derivative being represented by the general formula (II): ##STR2## wherein X represents a halogen atom, an alkyl group having 1 to 5 carbon atoms, a haloalkyl group, a phenyl group, a cyano group, or a nitro group, Xs being either the same or different from each other; n represents an integer of 0 to 5; A represents a nitrogen atom or CH; and R.sub.1 and R.sub.2 respectively represent a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, and a diluent or a carrier which is medically or veterinarily acceptable.
机译:本文公开了由通式(I)表示的唑衍生物或其盐:其中X代表卤原子,具有1-5个碳原子的烷基,卤代烷基,苯基,氰基或硝基,Xs彼此相同或不同; n表示1〜5的整数。 A代表氮原子或CH; R 1和R 2中的一个代表具有1至5个碳原子的烷基,另一个代表氢原子或具有1至5个碳原子的烷基,条件是当n为1或在图2中,X不代表卤素原子,具有1至5个碳原子的烷基或苯基以及包含有效量的唑衍生物或其医学或兽医学上可接受的盐的杀真菌剂,所述唑衍生物由通式表示(II):其中X表示卤素原子,具有1至5个碳原子的烷基,卤代烷基,苯基,氰基或硝基,Xs相同或不同。彼此之间n表示0〜5的整数。 A代表氮原子或CH; R 1和R 2分别代表氢原子或具有1-5个碳原子的烷基,以及医学上或兽医学上可接受的稀释剂或载体。

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