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Method of Checking the Rate of Removal of Pyrogenic Substrates, in Particular Viruses, from Organic Material
Method of Checking the Rate of Removal of Pyrogenic Substrates, in Particular Viruses, from Organic Material
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机译:检查从有机材料中去除特定病毒中热原质的速率的方法
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摘要
In order to check the rate of removal of pyrogenic substances, in particular viruses, from organic material, the material to be purified is passed through an ultra-filter or an ultra-filtration unit whose virus-removal rate has already been determined by passing viruses of the $i(Leviviridae) family or other, comparable, small bacteriophages through the filter or filtration unit, the virus titre determined before and after the filtration operation and the virus-removal rate thus calculated. Before or after determining the virus-removal rate, a given pressure is applied to the filter or filtration unit in a gas pressure-hold test, and the decrease in pressure over a given period measured. After filtration of the biological material, the rate of virus removal by the filter is checked by repeating the pressure-hold test.
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