BIOLOGICALLY ACTIVE AMPHIPHILIC PEPTIDES AND METHOD OF INHIBITING GROWTH OF TARGET CELLS, VIRUS OR VIRALLY-INFECTED CELL

摘要

Disclosed is a biologically active amphiphilic peptide which according to the aspect of the present invention comprises any of the following basic structures X1 to X7 wherein: X1 is [R1-R2-R2-R3-R1-R2-R2] -n ; X2 is - [R2-R2-R3-R1-R2-R2-R1] n; X3 is - [R2-R3-R1-R2-R2-R1-R2] n; X4 is - [R3-R1-R2-R2-R1-R2-R2] n; X5 is - [R1-R2-R2-R1-R2-R2-R3] -n; X6 is - [R2-R2-R1-R2-R2-R3-R1] n; and X7 is - [R2-R1-R2-R2-R3-R1-R2] n; wherein R1 is a basic hydrophilic amino acid, R2 is a hydrophobic amino acid, R3 is a neutral hydrophilic amino acid, basic or hydrophobic hydrophilic and n is from 2 to 5. These peptide compositions are used to inhibit growth of a target cell, d a virus or a virus-contaminated cell.