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A-associated H-antigens, monoclonal antibodies specific thereto and methods for employing the same in blood typing

机译:A相关的H抗原,其特异性单克隆抗体及其在血型鉴定中的应用方法

摘要

The present invention relates to antigens present in blood group A and blood group AB erythrocytes but absent in blood group B and blood group O erythrocytes. More specifically, the present invention relates to A-associated H-antigens having the following structure: wherein X is a sugar residue and n = O or a positive integer and wherein R is a primary amino group containing material selected from the group consisting of a polypeptide, a primary amino group containing lipid and primary amino group containing support; monoclonal antibodies specific thereto and methods for employing the same in blood typing.
机译:本发明涉及存在于A血型和AB血型的红细胞中但不存在于B血型和O血型的红细胞中的抗原。更具体地,本发明涉及具有以下结构的A相关的H抗原: 其中X是糖残基且n = O或正整数,且其中R是选自多肽,含伯氨基的脂质和含伯氨基的载体中的含伯氨基的物质;特异的单克隆抗体及其在血型鉴定中的应用方法。

著录项

  • 公开/公告号EP0274847B1

    专利类型

  • 公开/公告日1993-03-31

    原文格式PDF

  • 申请/专利权人 THE BIOMEMBRANE INSTITUTE;

    申请/专利号EP19870310571

  • 发明设计人 CLAUSEN HENRIK;

    申请日1987-12-01

  • 分类号C07H3/06;C07K15/14;C12P21/00;C12N5/00;

  • 国家 EP

  • 入库时间 2022-08-22 05:06:43

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