Method for the preparation of high-affinity hapten-specific antibodies and a composition for the detection of haptens

摘要

The invention relates to a method for the preparation of high-affinity anti-hapten antibodies and to a composition for the determination of haptens with the aid of these antibodies. The method for the preparation of these high-affinity anti-hapten antibodies is characterised in that, in a first stage, an animal is immunised several times with a hapten-protein conjugate and, in the second stage, the animal is immunised several times with a mixture of up to 3 hapten-protein conjugates, where the conjugates contain the same hapten but different proteins.