INHIBITION OF 5-LIPOXYGENASE AND CYCLOOXYGENASE PATHWAY MEDIATED DISEASES

摘要

A method of dual inhibition of diseases induced by 5-lipoxygenase pathways and diseases mediated by cyclooxygenase pathways in a subject in need thereof comprising administering to said subject an effective amount of inhibition pathways of non-toxic 5-lipoxygenase or a non-toxic effective dose of inhibition of cyclooxygenase pathways of a diaryl substitution imidazole fused to a second heterocyclic ring pentagonal or hexagonal unsaturated containing a nitrogen bridgehead atom, said second pentagonal ring also containing an atom sulfur or oxygen or said hexagonal ring also containing a further nitrogen atom.