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METHOD OF PREPARING OF COMPLEX PLATINUM (II) COMPOUND WITH NATIVE DNA SHOWING ANTITUMOR ACTIVITY

机译:具有天然DNA显示抗肿瘤活性的复合铂(II)的制备方法

摘要

the invention u043au0430u0441u0430u0435u0442u0441u00a0 plates (2 +) complex compounds, in particular u043fu043eu043bu0443u0447u0435u043du0438u00a0 complex u0441u043eu0435u0434u0438u043du0435u043du0438u00a0 platinum (2 +) - dna with tumour u0430u043au0442u0438u0432u043du043eu0441 last year, that can be used in medicine. the increased activity and decreased toxicity of the target product.this is u0434u043bu00a0 reaction of cis - u0434u0438u0445u043bu043eu0440u0434u0438u0430u043cu0438 - u043du043eu043fu043bu0430u0442u0438u043du044b with u0434u0435u0437u043eu043au0441u0438u0440u0438u0431u043eu043du0443u043au043bu0435u0438u043du043eu0432u043eu0439 acid (extracted from the spleens of bovine animals, mark (a) in the presence of NaCI and u043du0430u0442u0440u0438u00a0 synthase in u043cu043eu043bu00a0u0440u043du043eu043c ratio 6: 4: 30: 3, heated to 78 + 0.5 & deg; c for 15 - 20 minutes in the aquatic environment. the product is 95 percent. the growth of tumours, with 100 percent survival rate of the animals. 2, table 2).
机译:本发明 u043a u0430 u0441 u0430 u0435 u0442 u0441 u00a0板(2 +)复杂化合物,尤其是 u043f u043e u043b u0443 u0447 u0435 u043d u043d u0438 u00a0复杂物 u0441 u043e u0435 u0434 u0438 u043d u0435 u043d u0438 u00a0铂金(2 +)-去年患有肿瘤 u0430 u043a u0442 u0438 u0432 u043d u043e u0441的dna,可用于药物。目标产品的活性增加和毒性降低。这是顺式的 u0434 u043b u00a0反应- u0434 u0438 u0445 u043b u043e u0440 u0434 u0438 u0430 u043c u0438- u043d u043e u043f u043b u0430 u0442 u0438 u043d u044b与 u0434 u0435 u0437 u043e u043a u0441 u0438 u0440 u0438 u0431 u043e u043d u043d u0443 u043a u043b u0435 u0 u043d u043e u0432 u043e u0439酸(从牛的脾脏中提取,在存在NaCI和 u043d u0430 u0442 u0440 u0438 u00a0合酶 u043c u043e u043b 比例为6:4:30:3,在水生环境中加热至78 + 0.5摄氏度,持续15-20分钟,产物为95%,肿瘤的生长率是100%动物的存活率百分比,表2,表2)。

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