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Substantial biomaterials for the adhesion of cells and tissues adhesion.

机译:大量生物材料对细胞和组织的粘附力。

摘要

A cell culturing system, methods for the preparation thereof, and methods for affixing other biologically active moieties to a substrate are provided. Said cell culturing system comprises: a substrate; a coating thereon of a sterile formulation comprising polyphenolic protein containing from about 35 to 100% by weight pure bioadhesive polyphenolic protein having the repeating decapeptide unit: wherein N is a whole number ranging from about 10 to about 100, wherein each X is independently selected from the group consisting of hydroxyl and hydrogen, and wherein each R is independently selected from the group consisting of hydrogen and methyl; viable cells affixed to said coated substrate; and a nutritive medium contacting said cells, whereby said cells perform normal metabolic cell functions.
机译:提供了一种细胞培养系统,其制备方法以及用于将其他生物活性部分附着于底物的方法。所述细胞培养系统包括:基底;无菌制剂在其上的涂层,其包含多酚蛋白,所述多酚蛋白包含具有重复的十肽单元的约35至100重量%的纯生物粘附性多酚蛋白:其中N为约10至约100的整数,其中每个X独立地选自羟基和氢组成的基团,其中每个R独立地选自氢和甲基;活细胞固定在所述涂覆的基底上;以及与所述细胞接触的营养培养基,由此所述细胞执行正常的代谢细胞功能。

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