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Diagnostic sample for the detection of predisposition for diabetes type 1.
Diagnostic sample for the detection of predisposition for diabetes type 1.
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机译:诊断样本,用于检测1型糖尿病的易感性。
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摘要
An oligonucleotide probe capable of specifically hybridizing with the gene sequence 3 min -GCGGGCRARGRGGGGGRGCAG-5 min or 5 min -CGCCCGATACACCCCCACGTC-3 min wherein A is adenine, C is cytosine, G is guanine, T is thymine, and R is thymine or uracil. The probe may include at least 15 sequential nucleotides selected from the sequence 5 min -GCCCGATACACCCCCACGT-3 min or 3 min -CGGGCRARGRGGGGGRGCA-5 min The probe may be labelled with a detectable marker, such as an enzyme or biotin, and may be supplied in a diagnostic kit in combination with: a substratum capable of adsorbing DNA or cells, a restriction enzyme, and/or a detergent.
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机译:能够与基因序列特异性杂交的寡核苷酸探针3分钟-GCGGGCRARGRGGGGGRGCAG-5分钟或5分钟-CGCCCGATACACCCCCACGTC-3分钟,其中A为腺嘌呤,C为胞嘧啶,G为鸟嘌呤,T为胸腺嘧啶,R为胸腺嘧啶或尿嘧啶。探针可以包含选自序列5 min -GCCCGATACACCCCCACGT-3 min或3 min -CGGGCRARGRGGGGGGGRGCA-5 min的至少15个连续核苷酸。探针可以用可检测的标记物标记,例如酶或生物素,并可以以一种诊断试剂盒,其结合有:能够吸附DNA或细胞的基质,限制酶和/或去污剂。
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