Method for determining the origin anatu00c8mica of a cell or cell population derived from the intestine of a indivu00ecduo, detection method to determine the origin anatu00c8mica of a cell or cell population derived from the intestine of a indivu00ecduo, detection system, a Storage legu00ecvel by computer, arrangement of nucleic acid, use of an arrangement.Method for determining the beginning or predisposition to the beginning of a cellular abnormality or a condition destinguida by a cellular abnormality in the large intestine, diagnostic kit for testing biological samples

摘要

Method for determining the origin anatu00c8mica of a cell or cell population derived from the intestine of a indivu00ecduo, detection method to determine the origin anatu00c8mica of a cell or cell population derived from the intestine of a indivu00ecduo, detection system, a Storage legu00ecvel by computer, arrangement of nucleic acid, use of an arrangement.Method for determining the beginning or predisposition to the beginning of a cellular abnormality or a condition distinguished by a cellular abnormality in the large intestine, diagnostic kit for testing biological samples.The present invention relates in general to a series of molecules of nucleic acid, the profiles of expression of which characterize the anatomical origin of the cell or population of cells within the large intestine.More particularly, the present invention relates to a series of nucleic acid molecules, the expression of profiles which characterize the origin proximal or distal to the cell or population of cells within the large intestine.The profiles of expression of this invention are useful in a range of applications including, but not limited to determine the anatomical origin of the cell or population of cells that were derived from the intestine.In addition, since the progression of normal cell is often characterized by dedifferentiation, the method of this invention also provides a means of identifying the cellular abnormality based on the expression of a profile of expression is incorrect with respect to that which must be R expressed by cells object when viewed their anatomical location within the colon.Therefore, this aspect of the invention provides a valuable means of identifying the existence of colu00f3nicas cells of the large intestine, these being indicative of an abnormality in the large intestine such as the beginning or pre disposal to the beginning of the condition as a neoplasm Colorectal.