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New phenylimidazolidines, their process of preparation, their application as medicinal products and the pharmaceutical compositions containing them.

机译:新的苯基咪唑烷,它们的制备方法,它们作为医药产品的用途以及含有它们的药物组合物。

摘要

Products of formula (I): IMAGE in which: R1 denotes cyano, nitro or halogen, R2 denotes trifluoromethyl or halogen; the group -A-B- is chosen from the radicals IMAGE in which X denotes oxygen or sulphur and R3 is chosen from: - a hydrogen - alkyl, alkenyl, alkynyl, aryl or arylalkyl, optionally substituted; Y denotes oxygen or sulphur or NH, with the exception of the products in which: the group -A-B- denotes the radical IMAGE in which X denotes oxygen, R3 denotes hydrogen, Y denotes oxygen or NH, R2 denotes halogen or trifluoromethyl and R1 denotes nitro or halogen; the preparation, their application as medications and especially antiandrogens.
机译:式(I)的产物:<图像>其中:R1表示氰基,硝基或卤素,R2表示三氟甲基或卤素; -A-B-基团选自基团,其中X表示氧或硫,R 3选自:-氢<-烷基,烯基,炔基,芳基或芳基烷基,任选地被取代; Y表示氧或硫或NH,但以下产物除外:-AB-基团表示基团,其中X表示氧,R 3表示氢,Y表示氧或NH,R 2表示卤素或三氟甲基, R1表示硝基或卤素;制剂,它们作为药物特别是抗雄激素的应用。

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