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Compositions for the treatment of infection and diseases caused by hepatitis B virus (HBV).

机译:用于治疗由乙型肝炎病毒(HBV)引起的感染和疾病的组合物。

摘要

The present invention relates to a pharmaceutical composition for the treatment of infection or disease caused by the hepatitis B virus which comprises an amount of 1- (2'-deoxy-2'-fluoro-beta-D -arabinofuranosyl) -5-iodouracil (FIAU), a derivative which corresponds to a precursor of FIAU or a derivative which corresponds to a metabolite of FIAU, sufficient to provide a weak but effective antiviral dosage of FIAU, of its precursor or its metabolite, between about 0.05 and about 1 mg / kg-day, and a pharmaceutically acceptable carrier, its preparation process and its use for the treatment of diseases caused by HBV.
机译:本发明涉及用于治疗由乙型肝炎病毒引起的感染或疾病的药物组合物,其包含一定量的1-(2'-脱氧-2'-氟-β-D-阿拉伯呋喃糖基)-5-碘尿嘧啶( (FIAU),相当于FIAU前体的衍生物或相当于FIAU代谢物的衍生物,足以为其前体或代谢物提供弱但有效的FIAU抗病毒剂量,约0.05至约1 mg /千克/天,以及药学上可接受的载体,其制备方法及其在治疗由HBV引起的疾病中的用途。

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