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Compositions intended for the treatment of infections and diseases caused by hepatitis b virus (hbv).

机译:用于治疗由乙型肝炎病毒(hbv)引起的感染和疾病的组合物。

摘要

The present invention relates to pharmaceutical compositions useful for the treatment of subjects suffering from an infection or disease caused by the hepatitis B virus (HBV). In particular, it has been discovered that the administration of low dosage amounts of 1-(2'-deoxy-2'-fluoro- beta -D-arabinofuranosyl)-5-iodouracil (FIAU) to humans chronically infected with HBV is effective to reduce drastically circulating markers associated with HBV. The present invention is also directed to methods of the preparation of pharmaceutical antiviral compositions. IMAGE
机译:本发明涉及用于治疗由乙型肝炎病毒(HBV)引起的感染或疾病的受试者的药物组合物。特别是,已发现向慢性感染HBV的人服用低剂量的1-(2'-脱氧-2'-氟-β-D-阿拉伯呋喃糖基)-5-碘尿嘧啶(FIAU)减少与HBV相关的急剧循环的标志物。本发明还涉及药物抗病毒组合物的制备方法。 <图像>

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