PRODUCTION OF MONOCLONAL ANTIBODY PRODUCING CELL LINE, MONOCLONAL ANTIBODY PRODUCING CELL LINE AND MONOCLONAL ANTIBODY

摘要

PURPOSE: To provide a new monoclonal antibody producing cell line which produces monoclonal antibody useful for the detection of cocaine or its derivative with high sensitivity by immunoassay. ;CONSTITUTION: The monoclonal antibody producing cell line is obtained by fusing a mouse spleen cell sensitized with an antigen of a conjugate composed of a compound of formula (n is an integer of Z ≥1) and a protein to a cell line derived from a myeloma and screening the fused cells. The immunoglobulin produced in the supernatant of the cell line culture specifically combines to cocaine or its derivative.;COPYRIGHT: (C)1994,JPO&Japio