Analog Method of therapeutically useful oksodibentsoksepiini- and oksotienobentsoksepiinialkyyliamiini- and preparing -alkaanihappoamidijohdannaisten

摘要

This invention relates to N-hydroxy-dibenz[b,e]oxepinalkylamines, N-hydroxy-dibenz[b,e]oxepinalkanoic acid amides and related heterocyclic analogues of the formula CHEM where X together with the carbon atoms to which it is attached forms a benzene or thiophene ring; W and Z are independently hydrogen, halogen, loweralkyl, or trifluoromethyl, R1 is hydrogen, loweralkyl, or acyl; R2 is hydrogen, loweralkyl, cycloalkyl, arylloweralkyl or acyl; m is 0 or 1 and n is an integer of 0 to 12 and the pharmaceutically acceptable salts thereof. The compounds of this invention exhibit dermatological and analgesic activity.