PROCESS FOR DETERMINATION, BY MEANS OF FREE RADICALS, OF ANTI-OXIDANT PROPERTIES OF CELLS OF A LIVING ORGANISM OR POTENCIALLY AGRESSIVE AGENT

摘要

PCT No. PCT/FR90/00061 Sec. 371 Date Sep. 17, 1990 Sec. 102(e) Date Sep. 17, 1990 PCT Filed Jan. 26, 1990 PCT Pub. No. WO90/08955 PCT Pub. Date Aug. 9, 1990.The present invention relates to a novel method of assaying or evaluating the antioxidizing activities of a living organism or a potentially aggressive agent, said method, which comprises using free radicals as a means of inducing cell lysis, being characterized in that 1) a free radical generator is brought into contact, in an appropriate liquid biological medium, with a cell material selected from the group consisting of (a) human, animal and plant cells, (b) fragments of said cells, and (c) synthetic walls and fragments thereof containing liposomes, said cell material having first been contaminated with a potentially aggressive agent; 2) the release of free radicals from said free radical generator is induced; and 3) the lysis of the cell material by the free radicals is evaluated by comparison with a control containing said cell material which has not been contaminated.