首页> 外国专利> Deletion mutants of bovine herpes virus type 1, vaccines based on these mutants, and diagnostic kits for the detection of bovine herpes virus type 1

Deletion mutants of bovine herpes virus type 1, vaccines based on these mutants, and diagnostic kits for the detection of bovine herpes virus type 1

机译:1型牛疱疹病毒的缺失突变体,基于这些突变体的疫苗,以及用于检测1型牛疱疹病毒的诊断试剂盒

摘要

The present invention relates to a deletion mutant of bovine herpes virus type 1 which presents a deletion in the glycoprotein gE gene. The mutant can also present a deletion in the thymidine kinase gene and/or in the glycoprotein gI gene, or present an insertion of a heterologous gene; to a recombinant nucleic acid which includes the gE gene or a part thereof; to the glycoprotein gE, peptides based thereon and complexes formed by the glycoproteins gE and gI, and antibodies against them; to vaccines and diagnostic kits which include any one of these materials.
机译:本发明涉及1型牛疱疹病毒的缺失突变体,其在糖蛋白gE基因中缺失。该突变体还可以在胸苷激酶基因和/或糖蛋白gI基因中存在缺失,或存在异源基因的插入。包含gE基因或其一部分的重组核酸;糖蛋白gE,基于其的肽以及由糖蛋白gE和gI形成的复合物,以及针对它们的抗体;包括这些材料中任何一种的疫苗和诊断试剂盒。

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