compositions containing bafilomycina for inhibition of vacuolation induced by helicobacter pylori

摘要

The activity of inhibitors of vacuolar-type H+-ATPases in the inhibition of vacuolation induced by (Helicobacter pylori) is disclosed. Preferred agents are the macrolide antibiotics bafilomycins A1, A2, B1, B2, C1, C2 and D, especially bafilomycin A1. The use of such compounds in the treatment of diseases, including peptic ulceration, is claimed.