A method for preparing crystalline cefadroxil monohydrate.

摘要

THE INVENTION RELATES TO A METOD FOR PREPARING CRYSTALLINE MONOHYDRATE cefadroxil. Under this method SOLVENT cefadroxil ISOPROPYL ALCOHOL IS MORTERADO containing less than 6% A 18% W / W of water at a temperature ENTITY +45 +55 CY C: Cefadroxil Monohydrate ISOLATED lens is filtered. SOME OF THE SOLVENT cefadroxil CAN BE USED ARE NEW: they are prepared for A / ADIR DIMETILACETAMIDE, N-methyl-2-pyrrolidone O monomethylformamide AQUEOUS SOLUTION TO A cefadroxil at pH between 5.5 and 6.