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Expression of pertussis holotoxin in bordetella pertussis
Expression of pertussis holotoxin in bordetella pertussis
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机译:百日咳全毒素在百日咳博德特氏菌中的表达
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摘要
The invention relates to a cloned region of the Bordetella pertussis genome located 3' of the ptx operon encoding factors required for expression, assembly or secretion of pertussis holotoxin. Methods for obtaining increased levels of holotoxin production using homologous and heterologous hosts are also described.
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