Human growth hormone gene expression vector and method for producing human growth hormone using the same

摘要

The present invention relates to an expression vector comprising an operable gene and a yeast-derived alpha factor precursor sequence, a human growth hormone gene and a termination gene, a yeast transformed with such an expression vector, and a yeast transformed therewith to express human growth hormone According to the present invention, a human growth hormone gene is linked to an alpha factor precursor sequence derived from a yeast in advance and expressed together in a yeast. Thus, a natural human being produced in a human whose amino terminal methionine of human growth hormone is originally removed It has the advantage of producing biologically equivalent proteins with growth hormone.